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In immunocompromised including HIV-infected patients being treated for intestinal strongyloidiasis, repeated courses of therapy may be necessary.

Adequate and well-controlled clinical trials have not been conducted in such patients to determine the optimal dosing regimen.

Several treatments, i. Control of extraintestinal strongyloidiasis in these patients is difficult, and suppressive therapy, i.

Ivermectin is extensively metabolized in the liver and should be used cautiously in patients with hepatic disease.

Dosage adjustments may be needed, although specific recommendations are not currently available. The manufacturer does not recommend that ivermectin treatment be excluded in patients with liver disease.

Clinical trials of ivermectin did not include sufficient numbers of patients aged 65 and over to determine whether they respond differently from younger patients.

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The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of Ivermectin Topical Application that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

Ivermectin is well tolerated compared to other microfilaricidal agents i. Adverse reactions i. Adverse effects tend to occur with lesser frequency during periods of retreatment.

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If you are taking ivermectin to treat onchocerciasis, you may also experience the following side effects. Some side effects can be serious.

If you experience any of these symptoms, call your doctor immediately:. Ivermectin may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

Some side effects of ivermectin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine.

Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

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